3 min read522 words

Is the Man of Sin, the Final Antichrist the Pope?

Login to save this to your study library.

Answered by True Bible Teachings AI on 5/4/2026

1) Direct Answer
Yes. The Bible shows the final Antichrist—the “man of sin,” the “son of perdition”—as the papal office, culminating in a last-day pope who will head the world church-system and be Satan’s final instrument.

2) Scriptural Explanation
- 2 Thessalonians 2:3-4,8: The man of sin sits “in the temple of God,” shows himself that he is God, and will be destroyed by the appearing of the Lord. He takes a place in the church, claiming divine prerogatives.
- Revelation 17:1-6,9,18: A woman (a church) sits on many waters (peoples), is arrayed in purple and scarlet, decked with gold, drunk with the blood of saints, sits on seven mountains, and is “that great city which reigns over the kings of the earth.” That is a church-city power seated on seven hills, ruling over kings—a perfect picture of the Roman church system.
- Daniel 7:8,20-25: The “little horn” speaks great words, persecutes the saints, and “thinks to change times and laws.” This is the same blasphemous, persecuting power that rises out of the fourth beast (Rome).
- Revelation 13:1-8: The sea-beast receives global worship and blasphemes God; it makes war with the saints and overcomes them. This is the same Roman power in its religious-political form.
- Revelation 13:11-17: A second power enforces worship of the first beast and controls buying and selling—the mark system. So worship, law, and economy come under a church-state image that serves the first beast.
- John 17:12 with 2 Thessalonians 2:3: The title “son of perdition” is used for Judas and the end-time man of sin—both end with Satanic possession and open betrayal.

3) Simple Clarifying Logic
- In prophecy, a woman represents a church; a beast is a kingdom; mountains are prominent seats (hills); horns are kings. Revelation describes a church that is also a city, seated on seven hills, ruling over kings, clothed in the very colors Scripture names, drunk with the blood of saints. That points to the Roman church system.
- The head of that system is a man. Paul says he sits in the temple of God, taking God’s place among God’s people; John says the world will be compelled to worship under his authority with economic pressure. That is exactly a papal, worldwide religious headship turning into a global, enforced worship system.
- The Bible ties it all together: Rome (Daniel 7; Revelation 13, 17), a church-city on seven hills (Revelation 17), a man claiming divine place (2 Thessalonians 2), culminating in a final leader destroyed by the brightness of Christ’s coming (2 Thessalonians 2:8). That is the last-day pope in that office—the man of sin.

Short Reinforcing Statement
This is not against sincere people; God calls His own out of that system: “Come out of her, my people” (Revelation 18:4). The Scripture identifies the system and its head so believers won’t be deceived. Now notice, the Bible’s picture fits one power perfectly—no other church-city sits on seven hills and reigns over kings while claiming authority over the worship of the whole world.

What did the Laodicean Church Age (our age) Angel (- messenger) Say about this?

Ranked passages from the local William Branham sermon and Church Age Book database. Relevance is relative, not a statement of doctrinal certainty.

SermonRelevance 68

The Seal of Antichrist

Friday, the 11th of March 1955

55-0311 §44

Now, Paul picks it up in the 10th chapter of Hebrews. He said, "If we sin willfully..." Sin is unbelief, then if we disbelieve willfully, after the truth has been presented to us, there remains no more sacrifice for sin, but a fearful looking for the judgment." Then if the Gospel truth has been presented to people and they turn their head and reject it, then Satan takes them to the post. They're willing to serve their creeds and so forth, stick their ear out, and bore it in there, and you'll never be able to unders...

Read source context

SermonRelevance 67Broader match

The anointed ones at the end time

Sunday morning, the 25th of July 1965 at the Branham Tabernacle in Jeffersonville, Indiana, U.S.A.

65-0725M §174

Started where? This is false prophet (singular). False prophet, the first pope. And from there come up the whore and the mother of harlots, the whole thing. A false trinity was rising, not in the early days, wouldn't be made manifest in the early days, it went right on through with it. But when the seven seals be come and opened those mysteries and revealed them, that's when the frogs, three unclean spirits like frogs, come out to manifest themselves: a trinity doctrine against the truth. See where it come from? Se...

Read source context

SermonRelevance 64Broader match

The god of this evil age

Sunday morning, the 1st of August of 1965 at the Branham Tabernacle in Jeffersonville, Indiana, U.S.A.

65-0801M §85

And Satan will soon take his intellectual bride and exalt this great one which is the antichrist, the hierarchy, and set him upon a throne, and the whole world will wonder after him. And then Christ will come, and two cannot exist in the same time. And his kingdom will be taken. He will be destroyed, and Christ, the Word of God... Which the woman is a part of the man's body. They're not two; they're one. And the bride, church Word, of people called out from here and there for His namesake will unite in the body of...

Read source context

SermonRelevance 64

Seals 6: The Fourth Seal

Thursday, the 21st of March 1963

63-0321 §63

See the rider? The first place as an antichrist, he was death to begin with, but he was innocent then. Then he received a crown (a triple one), and when he did, then he united... Satan united his church and state because he was over both of them then. Antichrist was Satan in the form of a man. And then also, St. Matthew, I believe it is, the 4th chapter, tells us that Satan took Jesus, our Lord, up and showed Him the kingdoms of the world, all of them, in a moment of time, and the glory of them. Offered them to Him...

Read source context

Church Age BookRelevance 64

An Exposition Of The Seven Church Ages

Chapter 1: The Revelation Of Jesus Christ

CAB 1:E-48

That's why no man can ever come along and say the holy man is a pope or the holy man is a bishop or priest. The HOLY MAN is Christ, the Holy Spirit, in us. How dare the hierarchy declare the laity has no word to say? Each one has something to say. Each has a work, each has a ministry. The Holy Ghost came at Pentecost and separated Himself on each, that it might be fulfilled whereof Christ said, "At that day ye shall know that I am in My Father, and ye in Me and I in you." John 14:20.

Read source context