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Is the Man of Sin, the Final Antichrist the Pope?

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Answered by True Bible Teachings AI on 5/4/2026

1) Direct Answer
Yes. The Bible shows the final Antichrist—the “man of sin,” the “son of perdition”—as the papal office, culminating in a last-day pope who will head the world church-system and be Satan’s final instrument.

2) Scriptural Explanation
- 2 Thessalonians 2:3-4,8: The man of sin sits “in the temple of God,” shows himself that he is God, and will be destroyed by the appearing of the Lord. He takes a place in the church, claiming divine prerogatives.
- Revelation 17:1-6,9,18: A woman (a church) sits on many waters (peoples), is arrayed in purple and scarlet, decked with gold, drunk with the blood of saints, sits on seven mountains, and is “that great city which reigns over the kings of the earth.” That is a church-city power seated on seven hills, ruling over kings—a perfect picture of the Roman church system.
- Daniel 7:8,20-25: The “little horn” speaks great words, persecutes the saints, and “thinks to change times and laws.” This is the same blasphemous, persecuting power that rises out of the fourth beast (Rome).
- Revelation 13:1-8: The sea-beast receives global worship and blasphemes God; it makes war with the saints and overcomes them. This is the same Roman power in its religious-political form.
- Revelation 13:11-17: A second power enforces worship of the first beast and controls buying and selling—the mark system. So worship, law, and economy come under a church-state image that serves the first beast.
- John 17:12 with 2 Thessalonians 2:3: The title “son of perdition” is used for Judas and the end-time man of sin—both end with Satanic possession and open betrayal.

3) Simple Clarifying Logic
- In prophecy, a woman represents a church; a beast is a kingdom; mountains are prominent seats (hills); horns are kings. Revelation describes a church that is also a city, seated on seven hills, ruling over kings, clothed in the very colors Scripture names, drunk with the blood of saints. That points to the Roman church system.
- The head of that system is a man. Paul says he sits in the temple of God, taking God’s place among God’s people; John says the world will be compelled to worship under his authority with economic pressure. That is exactly a papal, worldwide religious headship turning into a global, enforced worship system.
- The Bible ties it all together: Rome (Daniel 7; Revelation 13, 17), a church-city on seven hills (Revelation 17), a man claiming divine place (2 Thessalonians 2), culminating in a final leader destroyed by the brightness of Christ’s coming (2 Thessalonians 2:8). That is the last-day pope in that office—the man of sin.

Short Reinforcing Statement
This is not against sincere people; God calls His own out of that system: “Come out of her, my people” (Revelation 18:4). The Scripture identifies the system and its head so believers won’t be deceived. Now notice, the Bible’s picture fits one power perfectly—no other church-city sits on seven hills and reigns over kings while claiming authority over the worship of the whole world.

What did the Laodicean Church Age (our age) Angel (- messenger) Say about this?

Ranked passages from the local William Branham sermon and Church Age Book database. Relevance is relative, not a statement of doctrinal certainty.

SermonRelevance 87

The Mark of the Beast

Thursday, the 13th of May 1954

54-0513 §50

Like everywhere in the Scripture, from the beginning of the Gentile plumb back from Genesis, I can prove that Babylon begin in Genesis and ends up in Revelation. Started out back there with Nimrod, the son of Ham, through idolatry, to bring idols in, to worship idols. And it's come right down through, and is so cunning in the last days till it takes on the name of Christianity, and still, idolatry! Didn't the great Saint Paul, in II Thessalonians say...? Let's just read it before we go any farther. II Thessalonians...

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SermonRelevance 85

The End Time

Sunday afternoon, the 7th of March 1954 at the Madison Square Garden in Phoenix, Arizona, U.S.A.

54-0307A §43

Now, Cain came and knelt at the gate---not an infidel. Many are thinking of the antichrist being Russia. Get it out of your minds. Never. The antichrist is religious. Jesus said, "The two spirits would be so close, it'd deceive the very elect if possible." Don't worry about Russia; they're just a bunch of atheists. Yes, but the antichrist sits right by you. That's the deceiver. Remember just the time that Jesus Christ come on the scene, the antichrist come on: Judas. About time Jesus revealed Himself as the Son of...

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SermonRelevance 83

Seals 5: The Third Seal

Wednesday, the 20th of March 1963

63-0320 §106

...stage he was innocent. And second (now, if you went a little bit higher, a little more than that), the second stage the Bible said he'd be given a crown. And they crowned a man---a superman. See, crowned him. Then the Bible didn't call him a pope. The Bible called him a false prophet. Why? Yeah, of course he must be a false prophet by his antichrist spirit that taught antichrist against the original Word. Because if you taught against the original Word, it was antichrist, and the Word is God.

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SermonRelevance 81

Church Ages, part 9: The ten virgins, and the 144,000

Sunday morning, the 11th of December 1960 at the Branham Tabernacle in Jeffersonville, Indiana, U.S.A.

60-1211M §125

Now watch what takes place here: And he caused all, both ... great, rich ... poor, free ... bond, to receive a mark in their right hand, or in their foreheads: And that no man might buy or sell, till he ... had the mark, or the name of the beast, or the number of his name. Here is wisdom. Let him that has understanding count the number of the beast: for it is ... number of a man; and his number is Six hundred threescore and six. ... which we know who that is. It's the hierarchy of Rome, pope. I've been right there...

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SermonRelevance 77Broader match

Daniel 9: Daniel's Seventy Weeks

Sunday, the 6th of August of 1961 at the Branham Tabernacle in Jeffersonville, Indiana, U.S.A.

61-0806 §95

Now, go on over here in Revelation 13 and show you that this man sits in a city, and the city sits on seven hills. And the numbers of the beast is 666. Wrote out in the Latin---Roman alphabet---is 666 is "Vicarius Filii Dei," which is "instead of the Son of God," on the pope's throne. And he's got a triple crown. And I've looked right at the crown, stood as close as my hand is to my face, like that, and seen the decked crown of the pope right there in the Vatican. Myself, stood and looked at it, to be sure I'd know...

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