3 min read522 words

Is the Man of Sin, the Final Antichrist the Pope?

Login to save this to your study library.

Answered by True Bible Teachings AI on 5/4/2026

1) Direct Answer
Yes. The Bible shows the final Antichrist—the “man of sin,” the “son of perdition”—as the papal office, culminating in a last-day pope who will head the world church-system and be Satan’s final instrument.

2) Scriptural Explanation
- 2 Thessalonians 2:3-4,8: The man of sin sits “in the temple of God,” shows himself that he is God, and will be destroyed by the appearing of the Lord. He takes a place in the church, claiming divine prerogatives.
- Revelation 17:1-6,9,18: A woman (a church) sits on many waters (peoples), is arrayed in purple and scarlet, decked with gold, drunk with the blood of saints, sits on seven mountains, and is “that great city which reigns over the kings of the earth.” That is a church-city power seated on seven hills, ruling over kings—a perfect picture of the Roman church system.
- Daniel 7:8,20-25: The “little horn” speaks great words, persecutes the saints, and “thinks to change times and laws.” This is the same blasphemous, persecuting power that rises out of the fourth beast (Rome).
- Revelation 13:1-8: The sea-beast receives global worship and blasphemes God; it makes war with the saints and overcomes them. This is the same Roman power in its religious-political form.
- Revelation 13:11-17: A second power enforces worship of the first beast and controls buying and selling—the mark system. So worship, law, and economy come under a church-state image that serves the first beast.
- John 17:12 with 2 Thessalonians 2:3: The title “son of perdition” is used for Judas and the end-time man of sin—both end with Satanic possession and open betrayal.

3) Simple Clarifying Logic
- In prophecy, a woman represents a church; a beast is a kingdom; mountains are prominent seats (hills); horns are kings. Revelation describes a church that is also a city, seated on seven hills, ruling over kings, clothed in the very colors Scripture names, drunk with the blood of saints. That points to the Roman church system.
- The head of that system is a man. Paul says he sits in the temple of God, taking God’s place among God’s people; John says the world will be compelled to worship under his authority with economic pressure. That is exactly a papal, worldwide religious headship turning into a global, enforced worship system.
- The Bible ties it all together: Rome (Daniel 7; Revelation 13, 17), a church-city on seven hills (Revelation 17), a man claiming divine place (2 Thessalonians 2), culminating in a final leader destroyed by the brightness of Christ’s coming (2 Thessalonians 2:8). That is the last-day pope in that office—the man of sin.

Short Reinforcing Statement
This is not against sincere people; God calls His own out of that system: “Come out of her, my people” (Revelation 18:4). The Scripture identifies the system and its head so believers won’t be deceived. Now notice, the Bible’s picture fits one power perfectly—no other church-city sits on seven hills and reigns over kings while claiming authority over the worship of the whole world.

What did the Laodicean Church Age (our age) Angel (- messenger) Say about this?

Ranked passages from the local William Branham sermon and Church Age Book database. Relevance is relative, not a statement of doctrinal certainty.

SermonRelevance 77

Seals 4: The Second Seal

Tuesday, the 19th of March 1963

63-0319 §44

These people who think that the Jews are the antichrist, they are certainly a million miles off the line. Don't you never think the Jews are an antichrist. Their eyes were blinded purposely that we might have a way to get in, giving us a time of repentance. But the antichrist is a Gentile. Certainly it is. An impersonator of the truth, anti---against. Now, this great superman---oh, how he become a great man, and then finally was throned. Then after throned, he was crowned. And now, he ... after that he was worshipp...

Read source context

Church Age BookRelevance 75

An Exposition Of The Seven Church Ages

Chapter 6: The Thyatirean Church Age

CAB 6:E-22

"There is one mediator between God and men, the man Christ Jesus (the Son of God.)"I Timothy 2:5. But the pope of Rome has changed the Word. He made it, "one mediator between God and man (not men)". So now he mediates between the mediator and men. But there is no other mediator save the Son. The pope pronounces salvation through the church of Rome. But there is no salvation except through the Son of God. No wonder the eyes blaze in fiery judgment. No wonder the feet are like fine brass as He stands ready to trample...

Read source context

SermonRelevance 74

The Third Exodus

Sunday morning, the 30th of June 1963 at the Branham Tabernacle in Jeffersonville, Indiana, U.S.A.

63-0630M §72

But there raised up a pharaoh who didn't know Joseph. The same thing today. A man has raised up and took oath in the White House that will not swear to his oath---will not take his oath, that he believes in freedom of religion. What's this new pope saying? One---four things that he has. One of them is to unite the Protestant and the Catholic together. And to any intellectual person, that's the thing to do. But according to the Bible, it's the wrong thing to do, and the Bible said they would do that. (Let's go a lit...

Read source context

SermonRelevance 73

Is your life worthy of the Gospel?

Sunday evening, the 30th of June 1963 at the Branham Tabernacle in Jeffersonville, Indiana, U.S.A.

63-0630E §41

"One of the great ambitions," somebody give me the paper just now, this new pope has said, "is to unite the churches together." They'll do it just as certain as I'm standing here. And the Protestants fall for it. See? Because, the church... The Bible said, Paul, the prophet of the Lord, said, "That day will not come except there come a falling away, first, and then the... before the man of sin will be revealed. He that setteth in the temple of God, upholding himself, all that's above God; he, as God," forgiving sin...

Read source context

SermonRelevance 72

Seals 6: The Fourth Seal

Thursday, the 21st of March 1963

63-0321 §68

Now you see, he was cast out of the earth and becomes incarnate. As the antichrist spirit become incarnate into a man, that man changes from one thing to another---from an antichrist spirit to a false prophet, and then the beast comes into him. Just exactly like the church grows. His church went from antichrist to false prophet. And in the great age to come the beast that is to rise up... So the church comes the same way, through justification, sanctification, and the baptism of the Holy Ghost as Christ being in th...

Read source context